St. Louis is a major city in Missouri along the Mississippi River. Its iconic, 630-ft. Gateway Arch, built in the 1960s, honors the early 19th-century explorations of Lewis and Clark and America's westward expansion in general. Replica paddlewheelers ply the river, offering views of the arch. The Soulard district is home to barbecue restaurants and clubs playing blues music.

Slide into St Louis and revel in the unique vibe of the largest city in the Great Plains. Beer, bowling and baseball are some of the top attractions, but history and culture, much of it linked to the Mississippi River, are a vital part of the fabric. And, of course, there's the iconic Gateway Arch that you have seen in a million pictures; it's even more impressive in reality. Many music legends, including Scott Joplin, Chuck Berry, Tina Turner and Miles Davis, got their start here and jammin' live-music venues keep the flame burning.

This old city by the river is a sensational place for food and nightlife. Plan on adding an extra day or more to your trip, for time to explore.